Ovulation cycle

Across TCGA cell cohorts, RNA activity of the Ovulation cycle pathway is significantly associated with the RNA expression of multiple genes, with the BREAST cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are BDH1, ZNF232, and SMARCE1, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Ovulation cycle activity versus BDH1 in BREAST (Pearson r = 0.45).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	BDH1 →	+1.630	+0.235	.009	.001	3	5
BLOOD_Lymphoma	ZNF232 →	+0.985	+0.252	<.001	.001	3	5
BLOOD_Leukemia	SMARCE1 →	+0.544	+0.191	.002	<.001	3	4
BLOOD_Myeloma	WEE1 →	+1.188	+0.204	.001	.001	3	4
BREAST	LSM14B →	+0.623	+0.182	.003	<.001	3	4
BREAST	CENPU →	+0.861	+0.176	.009	.004	2	5

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0042698 vs BDH1 — BREAST

Explore this scatter interactively →