Psychomotor behavior

Across TCGA patient cohorts, RNA activity of the Psychomotor behavior pathway is significantly associated with the protein abundance of multiple proteins, with the LUAD cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are CCNK_S329, MLLT1_S292, and DPP4, each associated with the pathway in up to 8 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Psychomotor behavior activity versus CCNK_S329 in LUAD (Pearson r = 0.16).

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CCNK_S329 →	-1.507	-0.136	<.001	<.001	3	8
LUAD	MLLT1_S292 →	-1.602	-0.103	<.001	<.001	3	8
COAD	DPP4 →	+1.119	+0.140	<.001	<.001	3	7
LUAD	ZNF318_S2101 →	-1.110	-0.133	<.001	<.001	3	6
LUAD	PRRC2C_S2107 →	-1.472	-0.133	<.001	<.001	3	6
LUAD	SRSF11_S449 →	-1.921	-0.142	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0036343 vs CCNK_S329 — LUAD

Explore this scatter interactively →