Post-anal tail morphogenesis

pathway activity — cross-omics
GO:0036342Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Post-anal tail morphogenesis pathway is significantly associated with the RNA expression of multiple genes, with the LSCC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are MRPL13, C8orf33, and FCMR, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCMRPL13 →+0.645+0.715<.001<.00135
BRCAC8orf33 →+0.577+0.358<.001.00135
LSCCFCMR →-0.648-0.548<.001<.00135
LSCCMEF2C →-0.706-0.675<.001.00435
UCECNRBP2 →+0.573+0.432.005.00434
UCECUSP13 →+0.569+0.425<.001.00634
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

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