Cell migration involved in metanephros development

pathway activity — cross-omics
GO:0035788Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Cell migration involved in metanephros development pathway is significantly associated with the RNA expression of multiple genes, with the UCEC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are GYPC, SNORD113-9, and CDH13, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECGYPC →+0.628+0.635.003.00934
LSCCSNORD113-9 →+1.140+0.544<.001.00234
HNSCCDH13 →+0.779+0.761.001.00533
CCRCCLRRC17 →+1.059+0.400<.001.00733
CCRCCGALNT15 →+2.528+0.235<.001<.00124
CCRCCHSPA12B →+1.252+0.389<.001.00933
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration