Locomotory exploration behavior

Across TCGA patient cohorts, RNA activity of the Locomotory exploration behavior pathway is significantly associated with the RNA expression of multiple genes, with the CCRCC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are LINC02471, LINC01506, and MIR223HG, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Locomotory exploration behavior activity versus LINC02471 in CCRCC (Pearson r = 0.30).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	LINC02471 →	+1.920	+0.436	<.001	<.001	3	5
HNSC	LINC01506 →	+0.584	+0.394	<.001	<.001	3	5
HNSC	MIR223HG →	+0.769	+0.350	<.001	.001	3	5
LSCC	PEBP4 →	+1.589	+0.969	<.001	<.001	3	4
LSCC	LRRK2 →	+1.396	+0.942	<.001	<.001	3	4
LUAD	LINC02555 →	+1.125	+0.420	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0035641 vs LINC02471 — CCRCC

Explore this scatter interactively →