Obsolete ncRNA catabolic process

pathway activity — cross-omics
GO:0034661Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Obsolete ncRNA catabolic process pathway is significantly associated with the protein abundance of multiple proteins, with the OV cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are YME1L1, COL1A2, and ANTXR1, each associated with the pathway in up to 6 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVYME1L1 →-0.208-0.041.004.00536
BRCACOL1A2 →+0.532+0.027<.001<.00136
CCRCCANTXR1 →+0.551+0.038<.001<.00135
BRCAPHLDB1_S324 →+0.536+0.028.008<.00135
LSCCMAP9_S79 →+0.535+0.041<.001.00135
OVLAMB1 →+0.411+0.042.003.00135
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration