Carbohydrate transmembrane transport

Across TCGA cell cohorts, RNA activity of the Carbohydrate transmembrane transport pathway is significantly associated with the RNA expression of multiple genes, with the STOMACH cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are SLC2A1, AHNAK, and MYOF, each associated with the pathway in up to 12 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Carbohydrate transmembrane transport activity versus SLC2A1 in STOMACH (Pearson r = 0.72).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	SLC2A1 →	+2.513	+1.231	<.001	<.001	3	12
BREAST	AHNAK →	+1.110	+0.668	.002	.003	3	5
LIVER	MYOF →	+3.992	+2.036	<.001	<.001	3	5
STOMACH	NIBAN2 →	+2.131	+1.636	.003	<.001	3	5
LIVER	TCP11L2 →	+1.182	+1.548	<.001	<.001	3	5
SKIN	CASKIN1 →	-0.474	-1.340	.002	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0034219 vs SLC2A1 — STOMACH

Explore this scatter interactively →