Regulation of tissue remodeling

Across TCGA cell cohorts, RNA activity of the Regulation of tissue remodeling pathway is significantly associated with the RNA expression of multiple genes, with the BLOOD_Lymphoma cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are TCTA, MRPS10, and NCOA3, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Regulation of tissue remodeling activity versus TCTA in BLOOD_Lymphoma (Pearson r = 0.47).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	TCTA →	+0.841	+0.788	.003	.003	3	5
OESOPHAGUS	MRPS10 →	-0.692	-0.889	.006	.001	2	5
BLOOD_Lymphoma	NCOA3 →	+1.495	+1.234	.001	<.001	3	4
URINARY_TRACT	RPL7L1 →	-0.689	-0.703	.003	.005	3	4
BLOOD_Lymphoma	ELMOD1 →	-1.023	-0.942	.001	.001	3	4
BLOOD_Lymphoma	SLC23A1 →	+1.840	+1.183	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0034103 vs TCTA — BLOOD_Lymphoma

Explore this scatter interactively →