Positive regulation of peptidyl-serine phosphorylation of STAT protein

pathway activity — cross-omics
GO:0033141Cross-omicsPROTEIN-MS → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Positive regulation of peptidyl-serine phosphorylation of STAT protein pathway is significantly associated with the immune infiltration of multiple features, with the GBM cohort showing a particularly strong set of associations.

The most reproducible pathway-associated features across cancer lineages are CD4+ Tcm, each associated with the pathway in up to 1 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated features by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner featureX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCD4+ Tcm →+0.008+0.257.012.01931
Each partner links to its Q-omics profile. Showing the 1 strongest associations by consensus.

Exploration