Locomotion involved in locomotory behavior

pathway activity — cross-omics
GO:0031987Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Locomotion involved in locomotory behavior pathway is significantly associated with the protein abundance of multiple proteins, with the GBM cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are YBX1_S165, HSPB6, and SNTA1, each associated with the pathway in up to 6 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMYBX1_S165 →-0.349-0.070.001<.00136
PDACHSPB6 →+0.481+0.024.003.00636
HNSCSNTA1 →+0.583+0.048<.001.00236
GBMHSPA12B →+0.227+0.041.004.00336
GBMKANK2 →+0.210+0.041.003.00336
LSCCAKAP12_S286 →+0.762+0.048.004.00136
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration