Peristalsis

pathway activity — cross-omics
GO:0030432Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Peristalsis pathway is significantly associated with the protein abundance of multiple proteins, with the CCRCC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are TBX2_S360, TBX2_S676, and TBX3_S456, each associated with the pathway in up to 7 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
CCRCCTBX2_S360 →+0.742+0.537<.001<.00137
OVTBX2_S676 →+0.776+0.523.001<.00137
BRCATBX3_S456 →+1.245+1.059<.001<.00135
BRCATBX3_S707 →+0.917+1.287<.001<.00135
UCECNES →+0.617+0.464<.001<.00135
GBMTBX2_S710 →+0.794+0.301<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration