Lipid glycosylation

pathway activity — cross-omics
GO:0030259Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Lipid glycosylation pathway is significantly associated with the protein abundance of multiple proteins, with the OV cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are SLC2A1, PIK3AP1, and LRRFIP1, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVSLC2A1 →-0.649-0.050.009.00735
BRCAPIK3AP1 →+0.527+0.081<.001<.00135
GBMLRRFIP1 →+0.225+0.052.009.00434
CCRCCARPC1B →+0.261+0.051.006.00125
BRCAZNF827_S760 →-0.389-0.071.005.00534
BRCACD14 →+0.400+0.049<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration