Glyceraldehyde-3-phosphate metabolic process

Across TCGA cell cohorts, RNA activity of the Glyceraldehyde-3-phosphate metabolic process pathway is significantly associated with the RNA expression of multiple genes, with the SOFT_TISSUE cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are TALDO1, GLA, and GSR, each associated with the pathway in up to 7 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Glyceraldehyde-3-phosphate metabolic process activity versus TALDO1 in SOFT_TISSUE (Pearson r = 0.51).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	TALDO1 →	+1.429	+0.233	.004	.005	2	7
OESOPHAGUS	GLA →	+1.267	+0.215	<.001	.002	3	5
LUNG_NSCLC_LUAD	GSR →	+1.394	+0.262	<.001	<.001	3	4
LUNG_NSCLC_LUAD	CBR1 →	+1.073	+0.208	<.001	.004	3	4
LUNG_NSCLC_LUAD	CBR3 →	+1.526	+0.252	<.001	<.001	3	4
SKIN	ZMYND19 →	+0.598	+0.202	.004	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0019682 vs TALDO1 — SOFT_TISSUE

Explore this scatter interactively →