Viral release from host cell

Across TCGA cell cohorts, RNA activity of the Viral release from host cell pathway is significantly associated with the RNA expression of multiple genes, with the LIVER cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are XYLB, NDUFAF6, and DNAJC22, each associated with the pathway in up to 6 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Viral release from host cell activity versus XYLB in LIVER (Pearson r = 0.79).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	XYLB →	+1.380	+0.277	.001	.003	3	6
PANCREAS	NDUFAF6 →	+0.646	+0.151	<.001	.001	3	5
OESOPHAGUS	DNAJC22 →	+1.824	+0.153	.009	.009	2	6
SKIN	SCLY →	+1.063	+0.247	.002	.001	3	5
LARGE_INTESTINE	SCP2 →	+1.036	+0.249	<.001	<.001	3	5
SKIN	STRA6 →	-3.548	-0.338	.003	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0019076 vs XYLB — LIVER

Explore this scatter interactively →