ATP transport

Across TCGA cell cohorts, RNA activity of the ATP transport pathway is significantly associated with the RNA expression of multiple genes, with the OVARY cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are CD47, PLAUR, and AAK1, each associated with the pathway in up to 9 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, ATP transport activity versus CD47 in OVARY (Pearson r = 0.59).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	CD47 →	+2.299	+0.220	<.001	<.001	3	9
BREAST	PLAUR →	+1.997	+0.239	.004	.004	3	8
BLOOD_Lymphoma	AAK1 →	+2.483	+0.326	<.001	<.001	3	7
LARGE_INTESTINE	NCEH1 →	+0.618	+0.160	.009	.004	3	7
CNS	APOL3 →	+2.364	+0.298	<.001	.001	3	7
CNS	ADPRH →	+0.983	+0.263	.007	.003	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0015867 vs CD47 — OVARY

Explore this scatter interactively →