ADP transport

Across TCGA cell cohorts, RNA activity of the ADP transport pathway is significantly associated with the RNA expression of multiple genes, with the OESOPHAGUS cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are FAR1, VPS29, and ITGAM, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The box plot shows the strongest association, FAR1 grouped by ADP transport-low versus -high activity in OESOPHAGUS.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	FAR1 →	-0.720	-0.984	.006	<.001	3	5
BLOOD_Leukemia	VPS29 →	-0.713	-1.605	<.001	<.001	3	4
BLOOD_Leukemia	ITGAM →	-2.188	-1.122	<.001	<.001	3	4
LARGE_INTESTINE	EIF2B2 →	-0.770	-1.036	<.001	.002	3	4
LARGE_INTESTINE	USP18 →	-1.003	-0.590	.004	.009	3	4
BLOOD_Myeloma	CCDC59 →	-1.076	-2.193	.002	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

FAR1 by ADP transport activity — OESOPHAGUS

Explore this box plot interactively →