Across TCGA patient cohorts, RNA activity of the Schwann cell proliferation pathway is significantly associated with the protein abundance of multiple proteins, with the PDAC cohort showing a particularly strong set of associations.
The most reproducible pathway-associated proteins across cancer lineages are PTPN14_S314, CCN1, and TNKS1BP1_S1138, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.
Each partner is linked to its corresponding Q-omics profile.