Glial cell proliferation

Across TCGA cell cohorts, RNA activity of the Glial cell proliferation pathway is significantly associated with the RNA expression of multiple genes, with the LIVER cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are ZNF572, ARMC10, and RNF121, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The box plot shows the strongest association, ZNF572 grouped by Glial cell proliferation-low versus -high activity in LIVER.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	ZNF572 →	+0.610	+0.305	.003	.008	3	5
UPPER_AERODIGESTIVE_TRACT	ARMC10 →	-0.759	-0.161	.001	.003	3	5
BLOOD_Myeloma	RNF121 →	+0.936	+0.332	.001	.001	3	4
BREAST	EEF2 →	-0.700	-0.160	.001	.006	3	4
STOMACH	MYO1A →	-3.113	-0.214	.001	.002	3	4
STOMACH	RNF215 →	+0.988	+0.265	.008	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

ZNF572 by Glial cell proliferation activity — LIVER

Explore this box plot interactively →