Post-embryonic animal morphogenesis

pathway activity — cross-omics
GO:0009886Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Post-embryonic animal morphogenesis pathway is significantly associated with the protein abundance of multiple proteins, with the OV cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are DIP2C, CALD1, and CNN2, each associated with the pathway in up to 7 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVDIP2C →+0.409+0.071<.001<.00137
UCECCALD1 →+0.829+0.104<.001<.00137
OVCNN2 →+0.736+0.067<.001<.00137
BRCACNN3_S323 →+0.737+0.057<.001.00137
BRCACOL1A2 →+0.702+0.068<.001<.00137
BRCADPYSL3 →+0.696+0.066<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration