Carbohydrate transport

Across TCGA patient cohorts, RNA activity of the Carbohydrate transport pathway is significantly associated with the protein abundance of multiple proteins, with the BRCA cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are RSU1, MAP1A, and MSRB3, each associated with the pathway in up to 7 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Carbohydrate transport activity versus RSU1 in BRCA (Pearson r = 0.22).

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	RSU1 →	+0.258	+0.016	.002	.001	3	7
GBM	MAP1A →	+0.335	+0.022	<.001	.001	3	7
GBM	MSRB3 →	+0.355	+0.028	.004	.002	3	7
LSCC	SRRM2_S2123 →	-0.321	-0.024	.001	.005	3	6
LSCC	SYNPO →	+0.360	+0.044	<.001	<.001	3	6
GBM	FEN1 →	-0.462	-0.043	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0008643 vs RSU1 — BRCA

Explore this scatter interactively →