Sulfate transport

pathway activity — cross-omics
GO:0008272Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Sulfate transport pathway is significantly associated with the protein abundance of multiple proteins, with the BRCA cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are DAP3, MRPL15, and MRPL53, each associated with the pathway in up to 6 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCADAP3 →+0.399+0.056<.001<.00136
BRCAMRPL15 →+0.379+0.061<.001<.00136
LSCCMRPL53 →+0.347+0.063<.001<.00136
LUADSLC25A10 →+0.580+0.075<.001<.00136
COADMRPL58 →+0.290+0.053.001<.00136
BRCAMRPS26 →+0.308+0.052<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration