Mesodermal cell migration

pathway activity — cross-omics
GO:0008078Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Mesodermal cell migration pathway is significantly associated with the RNA expression of multiple genes, with the BRCA cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are SNHG31, SNRPEP9, and STS, each associated with the pathway in up to 3 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCASNHG31 →-0.328-0.414.004.00333
PDACSNRPEP9 →-0.513-0.473.003.00233
CCRCCSTS →+0.395+0.395.007.00532
CCRCCARHGEF18 →+0.233+0.609<.001.00232
CCRCCTHEM6 →+0.427+0.646.007.00232
BRCANECTIN2 →+0.714+0.476.005.00332
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

Exploration