Visual behavior

Across TCGA patient cohorts, RNA activity of the Visual behavior pathway is significantly associated with the protein abundance of multiple proteins, with the LSCC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are CDKN1B, EIF4B_S93, and GNG7, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Visual behavior activity versus CDKN1B in LSCC (Pearson r = -0.06).

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CDKN1B →	-0.357	-0.041	<.001	<.001	3	5
LUAD	EIF4B_S93 →	+0.567	+0.029	<.001	<.001	3	5
LSCC	GNG7 →	-0.417	-0.026	<.001	<.001	3	5
HNSC	CEP350_S1648 →	-0.232	-0.043	.002	<.001	3	5
LSCC	CD38 →	-0.681	-0.036	<.001	<.001	3	5
HNSC	SASH3 →	-0.375	-0.032	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0007632 vs CDKN1B — LSCC

Explore this scatter interactively →