Visual behavior

Across TCGA patient cohorts, RNA activity of the Visual behavior pathway is significantly associated with the RNA expression of multiple genes, with the GBM cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are EOGT, LINC01511, and ANKRD20A5P, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Visual behavior activity versus EOGT in GBM (Pearson r = -0.15).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EOGT →	-0.343	-0.707	<.001	<.001	3	3
GBM	LINC01511 →	+0.230	+0.859	<.001	<.001	3	3
LSCC	ANKRD20A5P →	+0.328	+0.472	.008	.006	3	3
OV	CLCA2 →	-0.210	-0.540	<.001	<.001	3	3
GBM	OLIG2 →	+0.719	+0.458	.009	.008	3	3
OV	IGLV3-21 →	-3.185	-0.521	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0007632 vs EOGT — GBM

Explore this scatter interactively →