Visual behavior

Across TCGA cell cohorts, RNA activity of the Visual behavior pathway is significantly associated with the RNA expression of multiple genes, with the LUNG_SCLC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are NDRG4, TUBA1A, and RGS14, each associated with the pathway in up to 9 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Visual behavior activity versus NDRG4 in LUNG_SCLC (Pearson r = 0.53).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	NDRG4 →	+2.263	+0.122	<.001	<.001	3	9
BREAST	TUBA1A →	+2.907	+0.086	<.001	.001	3	7
LIVER	RGS14 →	+1.578	+0.107	.001	.001	3	7
BLOOD_Leukemia	HEXD →	+0.758	+0.103	.001	<.001	3	7
LARGE_INTESTINE	TCEA2 →	+1.383	+0.045	.007	.004	3	7
OVARY	NUP37 →	-0.885	-0.104	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0007632 vs NDRG4 — LUNG_SCLC

Explore this scatter interactively →