Visual behavior

Across TCGA cell cohorts, RNA activity of the Visual behavior pathway is significantly associated with the RNA expression of multiple genes, with the OVARY cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are APP, RGS16, and BCL9, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Visual behavior activity versus APP in OVARY (Pearson r = 0.53).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	APP →	+0.876	+0.929	.001	.009	3	4
OESOPHAGUS	RGS16 →	-1.260	-0.291	<.001	.002	3	4
BLOOD_Leukemia	BCL9 →	+1.659	+0.280	<.001	.002	3	3
KIDNEY	FPGT →	+0.653	+1.182	.003	.003	3	3
OVARY	ATRIP →	-0.833	-1.096	<.001	.001	3	3
LARGE_INTESTINE	ARL4C →	+2.711	+0.997	<.001	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0007632 vs APP — OVARY

Explore this scatter interactively →