Feeding behavior

Across TCGA cell cohorts, RNA activity of the Feeding behavior pathway is significantly associated with the RNA expression of multiple genes, with the OVARY cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are CPT1A, PRXL2A, and TUBB, each associated with the pathway in up to 9 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Feeding behavior activity versus CPT1A in OVARY (Pearson r = 0.66).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	CPT1A →	+2.210	+1.283	.001	<.001	3	9
BLOOD_Lymphoma	PRXL2A →	-3.001	-1.297	<.001	.001	3	5
SOFT_TISSUE	TUBB →	-0.461	-1.661	.004	<.001	3	5
LUNG_SCLC	DPF1 →	-1.226	-1.161	<.001	<.001	3	4
LUNG_SCLC	MSI1 →	-2.235	-0.864	.001	.007	3	4
LUNG_SCLC	C18orf25 →	-0.761	-1.137	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0007631 vs CPT1A — OVARY

Explore this scatter interactively →