Long-term memory

Across TCGA cell cohorts, RNA activity of the Long-term memory pathway is significantly associated with the RNA expression of multiple genes, with the PANCREAS cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are ARFRP1, FURIN, and MYO1D, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The box plot shows the strongest association, ARFRP1 grouped by Long-term memory-low versus -high activity in PANCREAS.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	ARFRP1 →	+0.418	+1.132	.002	.001	3	3
STOMACH	FURIN →	+1.805	+1.383	.005	.001	3	3
LIVER	MYO1D →	+2.357	+1.217	.001	<.001	3	3
PANCREAS	CASP4 →	+0.809	+1.181	.003	<.001	3	3
OVARY	RAB5IF →	+0.902	+1.214	.001	<.001	3	3
OVARY	DCST2 →	-0.523	-1.067	.002	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

ARFRP1 by Long-term memory activity — PANCREAS

Explore this box plot interactively →