Long-term memory

Across TCGA cell cohorts, RNA activity of the Long-term memory pathway is significantly associated with the RNA expression of multiple genes, with the BLOOD_Myeloma cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are PALD1, RAB11FIP4, and SERINC3, each associated with the pathway in up to 6 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Long-term memory activity versus PALD1 in BLOOD_Myeloma (Pearson r = -0.68).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	PALD1 →	-2.397	-1.454	.006	<.001	2	6
BLOOD_Myeloma	RAB11FIP4 →	-2.034	-1.804	.006	<.001	3	5
BREAST	SERINC3 →	+0.840	+0.883	.002	.007	3	5
LARGE_INTESTINE	THRAP3 →	-0.548	-0.845	<.001	.001	3	5
URINARY_TRACT	RGS17 →	+2.202	+1.940	<.001	<.001	3	4
SOFT_TISSUE	IRF1-AS1 →	+1.151	+1.217	.002	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0007616 vs PALD1 — BLOOD_Myeloma

Explore this scatter interactively →