Short-term memory

pathway activity — cross-omics
GO:0007614Cross-omicsRNA → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, RNA activity of the Short-term memory pathway is significantly associated with the RNA expression of multiple genes, with the SKCM cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are RCAN1, SERPINF1, and TNFAIP6, each associated with the pathway in up to 27 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Short-term memory activity versus RCAN1 in SKCM (Pearson r = 0.00).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMRCAN1 →+1.226+0.085<.001<.001327
KICHSERPINF1 →+2.291+0.108<.001<.001326
SARCTNFAIP6 →+2.441+0.106<.001<.001321
KICHC1R →+2.044+0.105<.001.001221
ACCC1S →+2.119+0.088<.001<.001221
KICHCOL1A1 →+2.454+0.085<.001.005221
Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0007614 vs RCAN1 — SKCM

Per-sample scatter of Short-term memory activity vs RCAN1 in SKCM.

Explore this scatter interactively →

Exploration