Embryo implantation

Across TCGA patient cohorts, RNA activity of the Embryo implantation pathway is significantly associated with the protein abundance of multiple proteins, with the OV cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are C8A, C1R, and C4BPB, each associated with the pathway in up to 8 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Embryo implantation activity versus C8A in OV (Pearson r = 0.41).

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	C8A →	+0.505	+0.045	.001	.004	3	8
GBM	C1R →	+0.537	+0.063	<.001	<.001	3	8
OV	C4BPB →	+0.809	+0.060	<.001	<.001	3	8
GBM	C6 →	+0.526	+0.056	<.001	<.001	3	8
CCRCC	CD93 →	+0.609	+0.066	<.001	<.001	3	8
OV	CFH →	+0.595	+0.053	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0007566 vs C8A — OV

Explore this scatter interactively →