Nucleotide transport

Across TCGA cell cohorts, RNA activity of the Nucleotide transport pathway is significantly associated with the RNA expression of multiple genes, with the OVARY cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are CD47, UBA7, and GOLGA5, each associated with the pathway in up to 11 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Nucleotide transport activity versus CD47 in OVARY (Pearson r = 0.65).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	CD47 →	+1.876	+0.235	.002	<.001	3	11
SKIN	UBA7 →	+1.631	+0.255	.008	.004	2	9
CNS	GOLGA5 →	+0.791	+0.288	.001	.002	3	7
CNS	ACTR10 →	+0.800	+0.302	<.001	<.001	3	7
CNS	KLHL23 →	-1.189	-0.313	<.001	<.001	3	7
OESOPHAGUS	SYTL2 →	+2.604	+0.216	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0006862 vs CD47 — OVARY

Explore this scatter interactively →