Across TCGA patient cohorts, RNA activity of the Mineralocorticoid biosynthetic process pathway is significantly associated with the protein abundance of multiple proteins, with the OV cohort showing a particularly strong set of associations.
The most reproducible pathway-associated proteins across cancer lineages are PEA15_S90, BLOC1S3_S89, and DAB2_S394, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.
Each partner is linked to its corresponding Q-omics profile.