Triglyceride metabolic process

Across TCGA patient cohorts, RNA activity of the Triglyceride metabolic process pathway is significantly associated with the protein abundance of multiple proteins, with the OV cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are TNS2_S102, RIF1_S782, and SF3B6, each associated with the pathway in up to 7 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Triglyceride metabolic process activity versus TNS2_S102 in OV (Pearson r = 0.40).

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TNS2_S102 →	+0.655	+0.019	<.001	.001	3	7
BRCA	RIF1_S782 →	-0.914	-0.033	.005	.001	3	6
BRCA	SF3B6 →	-0.290	-0.031	.001	<.001	3	6
BRCA	SUSD2 →	+0.633	+0.027	<.001	<.001	3	6
OV	ARHGAP15_S64 →	+1.006	+0.029	<.001	.004	3	6
BRCA	CAVIN1 →	+0.981	+0.037	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0006641 vs TNS2_S102 — OV

Explore this scatter interactively →