Triglyceride metabolic process

Across TCGA cell cohorts, RNA activity of the Triglyceride metabolic process pathway is significantly associated with the RNA expression of multiple genes, with the OVARY cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are LRRIQ3, EMB, and PRIM1, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The box plot shows the strongest association, LRRIQ3 grouped by Triglyceride metabolic process-low versus -high activity in OVARY.

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	LRRIQ3 →	+0.485	+1.111	.006	<.001	3	3
OVARY	EMB →	+1.437	+0.711	.008	.004	3	3
OVARY	PRIM1 →	+0.714	+0.758	.001	.002	3	3
BREAST	PSMD9 →	+0.473	+0.479	.001	.002	2	4
BONE	DMAC2 →	+0.830	+1.352	.003	.001	3	3
BLOOD_Lymphoma	RNMT →	-0.901	-1.463	.003	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

LRRIQ3 by Triglyceride metabolic process activity — OVARY

Explore this box plot interactively →