Glucose metabolic process

Across TCGA cell cohorts, RNA activity of the Glucose metabolic process pathway is significantly associated with the protein abundance of multiple proteins, with the URINARY_TRACT cohort showing a particularly strong set of associations.

The most reproducible pathway-associated proteins across cancer lineages are ALDOC, GPI, and ABCB6, each associated with the pathway in up to 17 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Glucose metabolic process activity versus ALDOC in URINARY_TRACT (Pearson r = 0.90).

Pathway-associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	ALDOC →	+3.278	+0.614	<.001	<.001	3	17
LUNG_NSCLC_LUSC	GPI →	+3.207	+0.391	.001	.003	3	14
URINARY_TRACT	ABCB6 →	+3.391	+0.489	<.001	.003	3	14
LUNG_NSCLC_LUSC	PGD →	+3.520	+0.238	.001	.003	3	14
URINARY_TRACT	ALDOA →	+2.862	+0.431	<.001	<.001	3	14
URINARY_TRACT	TKT →	+3.031	+0.396	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0006006 vs ALDOC — URINARY_TRACT

Explore this scatter interactively →