Across TCGA patient cohorts, RNA activity of the Gastric acid secretion pathway is significantly associated with the protein abundance of multiple proteins, with the GBM cohort showing a particularly strong set of associations.
The most reproducible pathway-associated proteins across cancer lineages are CAVIN1_Y308, KCNQ1_S27, and SOS1_S1275, each associated with the pathway in up to 4 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.
Each partner is linked to its corresponding Q-omics profile.