Oocyte maturation

Across TCGA cell cohorts, RNA activity of the Oocyte maturation pathway is significantly associated with the RNA expression of multiple genes, with the LUNG_SCLC cohort showing a particularly strong set of associations.

The most reproducible pathway-associated genes across cancer lineages are SLC36A1, BUD13, and TMEM209, each associated with the pathway in up to 5 cancer types. Since the analysis shows associations rather than directional relationships, both pathway-to-partner and partner-to-pathway views are reported.

Each partner is linked to its corresponding Q-omics profile. The scatter plot shows the strongest association, Oocyte maturation activity versus SLC36A1 in LUNG_SCLC (Pearson r = -0.34).

Pathway-associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (pathway→partner) and Y-score (partner→pathway) are standardized regression coefficients; both directions are reported because the association is undirected. The reported p-values are derived from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	SLC36A1 →	-0.792	-0.437	<.001	.002	3	4
BREAST	BUD13 →	+0.628	+0.697	<.001	<.001	3	4
STOMACH	TMEM209 →	+0.771	+0.361	.007	<.001	2	5
BLOOD_Leukemia	UBFD1 →	+0.778	+0.534	<.001	.002	3	4
BLOOD_Leukemia	CD68 →	-2.562	-0.365	.003	.004	2	5
BLOOD_Leukemia	RFC3 →	+0.613	+0.376	<.001	.003	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest associations by consensus.

GO:0001556 vs SLC36A1 — LUNG_SCLC

Explore this scatter interactively →