ZZZ3

Across TCGA patient cohorts, ZZZ3 protein abundance is significantly associated with the RNA expression of many other genes, with 6,169 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZZZ3-associated genes across cancer lineages are TFAP4, RABGGTB, and OMG. Each is linked with ZZZ3 in more than 2 cancer types. Because this analysis shows association rather than direction, both ZZZ3-to-partner and partner-to-ZZZ3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZZZ3 versus TFAP4 in LSCC, with a Pearson correlation of 0.45.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZZZ3→partner) and Y-score (partner→ZZZ3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TFAP4 →	+0.632	+0.249	<.001	<.001	3	3
BRCA	RABGGTB →	+0.415	+0.232	<.001	.001	3	3
OV	OMG →	+0.585	+0.909	.006	<.001	3	2
OV	SUSD3 →	-1.200	-1.094	.008	.008	3	2
HNSC	CLEC4E →	+0.909	+0.747	.001	.001	3	2
OV	FAM104B →	-0.435	-0.798	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,169 associations by consensus.

ZZZ3 vs TFAP4 — LSCC

Explore this scatter interactively →