ZZZ3

Across TCGA cell cohorts, ZZZ3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,819 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZZZ3-associated GO terms across cancer lineages are Zinc ion import into Golgi lumen, Protein modification by small protein removal, and Positive regulation of organelle assembly. Each is linked with ZZZ3 in more than 12 cancer types. Because this analysis shows association rather than direction, both ZZZ3-to-partner and partner-to-ZZZ3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Zinc ion import into Golgi lumen grouped by ZZZ3-low versus ZZZ3-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZZZ3→partner) and Y-score (partner→ZZZ3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Zinc ion import into Golgi lumen →	+0.071	+0.470	.004	.006	3	13
LUNG_NSCLC_LUSC	Protein modification by small protein removal →	+0.049	+0.745	.004	.002	3	13
LUNG_NSCLC_LUSC	Positive regulation of organelle assembly →	+0.070	+0.695	.003	.002	2	13
SOFT_TISSUE	Establishment of mitotic sister chromatid cohesion →	+0.118	+0.786	<.001	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	Positive regulation of centriole replication →	+0.140	+0.965	<.001	.001	3	11
UPPER_AERODIGESTIVE_TRACT	Mitotic recombination →	+0.092	+0.925	.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,819 associations by consensus.

Zinc ion import into Golgi lumen by ZZZ3 expression — SKIN

Explore this box plot interactively →