ZYG11B

Across TCGA patient cohorts, ZYG11B RNA expression is significantly associated with the protein abundance of many other proteins, with 18,714 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ZYG11B-associated proteins across cancer lineages are SDF2L1, MZB1, and RBSN. Each is linked with ZYG11B in more than 5 cancer types. Because this analysis shows association rather than direction, both ZYG11B-to-partner and partner-to-ZYG11B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZYG11B versus SDF2L1 in BRCA, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZYG11B→partner) and Y-score (partner→ZYG11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SDF2L1 →	-0.406	-0.528	<.001	<.001	3	6
GBM	MZB1 →	-1.076	-0.458	.001	.002	3	5
BRCA	RBSN →	+0.286	+0.696	<.001	<.001	3	5
GBM	TNFAIP8 →	-0.703	-0.325	<.001	<.001	3	5
LUAD	RPL12 →	-0.201	-0.430	<.001	<.001	3	5
GBM	RPL7 →	-0.459	-0.464	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,714 associations by consensus.

ZYG11B vs SDF2L1 — BRCA

Explore this scatter interactively →