ZYG11B

Across TCGA cell cohorts, ZYG11B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,009 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ZYG11B-associated GO terms across cancer lineages are Positive regulation of organelle assembly, Golgi vesicle transport, and Endosomal transport. Each is linked with ZYG11B in more than 16 cancer types. Because this analysis shows association rather than direction, both ZYG11B-to-partner and partner-to-ZYG11B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of organelle assembly grouped by ZYG11B-low versus ZYG11B-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZYG11B→partner) and Y-score (partner→ZYG11B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Positive regulation of organelle assembly →	+0.074	+1.051	<.001	<.001	3	17
OESOPHAGUS	Golgi vesicle transport →	+0.092	+0.793	<.001	<.001	3	17
LUNG_SCLC	Endosomal transport →	+0.061	+0.634	<.001	<.001	2	17
BONE	Cytosolic transport →	+0.069	+0.644	.006	.001	3	16
LIVER	Organelle transport along microtubule →	+0.069	+0.563	.004	<.001	3	15
LUNG_SCLC	Regulation of G1/S transition of mitotic cell cycle →	+0.063	+0.703	.002	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,009 associations by consensus.

Positive regulation of organelle assembly by ZYG11B expression — STOMACH

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