ZXDC

Across TCGA patient cohorts, ZXDC RNA expression is significantly associated with the protein abundance of many other proteins, with 13,817 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZXDC-associated proteins across cancer lineages are ACTL6A, HNRNPU, and WDR5. Each is linked with ZXDC in more than 5 cancer types. Because this analysis shows association rather than direction, both ZXDC-to-partner and partner-to-ZXDC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZXDC versus ACTL6A in LSCC, with a Pearson correlation of 0.51.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZXDC→partner) and Y-score (partner→ZXDC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ACTL6A →	+0.303	+0.347	<.001	<.001	3	6
GBM	HNRNPU →	+0.288	+0.323	<.001	<.001	3	6
LSCC	WDR5 →	+0.231	+0.420	<.001	<.001	3	6
LSCC	NONO →	+0.180	+0.438	<.001	<.001	3	6
GBM	PARP1 →	+0.311	+0.228	<.001	<.001	3	6
GBM	RPRD2 →	+0.272	+0.320	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,817 associations by consensus.

ZXDC vs ACTL6A — LSCC

Explore this scatter interactively →