ZXDC

Across TCGA patient cohorts, ZXDC protein abundance is significantly associated with the RNA expression of many other genes, with 10,093 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZXDC-associated genes across cancer lineages are CEP78, SNX4, and SEC22A. Each is linked with ZXDC in more than 3 cancer types. Because this analysis shows association rather than direction, both ZXDC-to-partner and partner-to-ZXDC results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZXDC versus CEP78 in HNSC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZXDC→partner) and Y-score (partner→ZXDC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	CEP78 →	+0.696	+0.443	<.001	.003	3	4
HNSC	SNX4 →	+1.091	+0.704	.001	<.001	3	3
HNSC	SEC22A →	+0.732	+0.529	<.001	<.001	3	3
LSCC	GTF2E1 →	+0.589	+0.447	<.001	<.001	3	3
HNSC	CCDC138 →	+0.692	+0.377	<.001	.001	3	3
HNSC	POGLUT1 →	+0.856	+0.505	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,093 associations by consensus.

ZXDC vs CEP78 — HNSC

Explore this scatter interactively →