Across TCGA patient cohorts, ZXDB mutation is significantly associated with the RNA expression of many other genes, with 3,264 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZXDB-associated genes across cancer lineages are MIR3973, RN7SKP245, and TMCC2-AS1. Each is linked with ZXDB in more than 2 cancer types. Because this analysis shows association rather than direction, both ZXDB-to-partner and partner-to-ZXDB results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZXDB→partner) and Y-score (partner→ZXDB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR3973 →	+0.182	+4.579	<.001	.003	3	3
LIHC	RN7SKP245 →	+0.109	+4.647	<.001	.007	3	2
LIHC	TMCC2-AS1 →	+0.053	+4.544	<.001	.009	3	2
LIHC	YWHAQP8 →	+0.158	+5.771	<.001	<.001	3	2
COAD	APOL3 →	+0.870	+3.459	.005	.005	3	2
COAD	EI24 →	+0.398	+3.459	.006	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,264 associations by consensus.

Exploration

ZXDB survival (RNA) · tumor vs normal (RNA) · all ZXDB data types