Across TCGA cell cohorts, ZXDB RNA expression is significantly associated with the RNA expression of many other genes, with 8,406 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZXDB-associated genes across cancer lineages are ZXDA, UBQLN2, and RLIM. Each is linked with ZXDB in more than 18 cancer types. Because this analysis shows association rather than direction, both ZXDB-to-partner and partner-to-ZXDB results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZXDB→partner) and Y-score (partner→ZXDB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	ZXDA →	+0.953	+0.843	<.001	<.001	3	19
UPPER_AERODIGESTIVE_TRACT	UBQLN2 →	+1.618	+1.099	<.001	<.001	3	16
LUNG_NSCLC_LUSC	RLIM →	+1.029	+0.813	<.001	<.001	2	17
SOFT_TISSUE	PHF8 →	+1.003	+0.630	<.001	<.001	3	15
OVARY	USP9X →	+1.418	+0.724	<.001	<.001	3	15
URINARY_TRACT	MBTPS2 →	+1.231	+0.977	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,406 associations by consensus.

Exploration

ZXDB survival (RNA) · tumor vs normal (RNA) · all ZXDB data types