Across TCGA patient cohorts, ZXDA mutation is significantly associated with the total protein of many other genes, with 71 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZXDA-associated genes across cancer lineages are eEF2, GAPDH, and N-Ras. Each is linked with ZXDA in more than 3 cancer types. Because this analysis shows association rather than direction, both ZXDA-to-partner and partner-to-ZXDA results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZXDA→partner) and Y-score (partner→ZXDA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	eEF2 →	+0.356	+2.841	.005	.033	3	4
COAD	GAPDH →	+0.817	+3.593	<.001	.001	3	3
COAD	N-Ras →	-0.134	-3.000	.032	.035	3	3
COAD	p53 →	-0.312	-3.000	.026	.034	3	3
COAD	Di-Ras3 →	-0.203	-3.169	.016	.018	3	3
UCEC	Caspase-7-cleavedD198 →	+0.457	+1.867	.011	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 71 associations by consensus.

Exploration

ZXDA survival (RNA) · tumor vs normal (RNA) · all ZXDA data types