ZWINT

Across TCGA cell cohorts, ZWINT RNA expression is significantly associated with the go_rna of many other GO terms, with 3,813 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ZWINT-associated GO terms across cancer lineages are Negative regulation of cell cycle process, Mitotic nuclear division, and Negative regulation of cell cycle phase transition. Each is linked with ZWINT in more than 19 cancer types. Because this analysis shows association rather than direction, both ZWINT-to-partner and partner-to-ZWINT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of cell cycle process grouped by ZWINT-low versus ZWINT-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ZWINT→partner) and Y-score (partner→ZWINT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Negative regulation of cell cycle process →	+0.084	+2.081	<.001	<.001	3	20
OESOPHAGUS	Mitotic nuclear division →	+0.111	+1.301	.004	<.001	3	20
BLOOD_Myeloma	Negative regulation of cell cycle phase transition →	+0.078	+1.608	<.001	.002	3	20
KIDNEY	Microtubule cytoskeleton organization involved in mitosis →	+0.103	+1.136	<.001	.001	3	20
OESOPHAGUS	Nuclear division →	+0.104	+1.619	.002	<.001	3	20
BONE	Replication fork processing →	+0.158	+1.855	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,813 associations by consensus.

Negative regulation of cell cycle process by ZWINT expression — BLOOD_Myeloma

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