ZWILCH

Across TCGA patient cohorts, ZWILCH mutation is significantly associated with the RNA expression of many other genes, with 1,870 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ZWILCH-associated genes across cancer lineages are RN7SL66P, LINC00457, and KRTAP9-8. Each is linked with ZWILCH in more than 1 cancer types. Because this analysis shows association rather than direction, both ZWILCH-to-partner and partner-to-ZWILCH results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL66P grouped by ZWILCH-low versus ZWILCH-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ZWILCH→partner) and Y-score (partner→ZWILCH) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RN7SL66P →	+0.151	+5.010	<.001	.009	3	2
CESC	LINC00457 →	+0.055	+5.201	<.001	.007	3	2
LUAD	KRTAP9-8 →	+0.164	+7.930	<.001	.008	3	2
UCEC	MIR425 →	+0.347	+2.040	.002	.008	3	2
UCEC	ONECUT3 →	+0.467	+2.276	.006	.005	3	2
UCEC	RNU6-1292P →	+0.268	+3.231	<.001	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,870 associations by consensus.

RN7SL66P by ZWILCH expression — CESC

Explore this box plot interactively →