ZUP1

Across TCGA patient cohorts, ZUP1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,449 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ZUP1-associated proteins across cancer lineages are MAP3K4, SYNCRIP, and VTA1. Each is linked with ZUP1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ZUP1-to-partner and partner-to-ZUP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ZUP1 versus MAP3K4 in GBM, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ZUP1→partner) and Y-score (partner→ZUP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	MAP3K4 →	+0.389	+0.415	<.001	.001	3	7
GBM	SYNCRIP →	+0.376	+0.467	<.001	<.001	3	6
OV	VTA1 →	+0.382	+0.520	.001	.004	2	7
COAD	PRKAR2A →	-0.267	-0.444	<.001	<.001	3	5
LSCC	MDN1 →	+0.333	+0.378	<.001	<.001	3	5
GBM	RNGTT →	+0.424	+0.470	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,449 associations by consensus.

ZUP1 vs MAP3K4 — GBM

Explore this scatter interactively →